Comparison of Ibuprofen and Dexamethasone Premedication on Inferior Dental Nerve Block in Irreversible Pulpitis

Aim: To compare premedication with dexamethasone as compared to ibuprofen in the effectiveness of IDNB lower molars asymptomatic irreversible pulpal infection. Study design: A Randomized Control Clinical Trial. Place & duration: Department Operative Dentistry, Akhtar Saeed Medical and Dental College, Lahore, from October 2022 November Methodology: total 30 cases each group were taken, using an expected success rate Dexamethasone Ibuprofen 38.2% 78% respectively, taking 5% level significance 80% power study. Therefore, sixty endodontic subjects taken divided into two equal groups thirty patients each, 1 was given 0.5 mg 2, 400 pre-medication prior therapy. Results: The results showed mean pain scores 24.38±15.41 35.63±18.74 2 (P<0.05). According score, 11 (36.7%) have score between 0.0-20 (successful) 21 (63.3%) has 21.0-100.0 (unsuccessful) mean±standard deviation 24.38±15.41. While 5 (16.7%) 25 (83.3%) 35.63±18.74. Conclusion: ibuprofen, increased inferior dental nerve block pulpitis. Keywords: IDNB, Irreversible pulpitis, Nerve block, Endodontics.